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Synthesizing literature

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Jump to navigation Jump to search This article is about artificial synthesis of organic compounds. This article needs additional citations for verification. Organic synthesis is a special branch of chemical synthesis and is concerned with the intentional construction of organic compounds. This section needs additional citations for verification. Each step of a synthesis involves a chemical reaction, synthesizing literature reagents and conditions for each of these reactions must be designed to give an adequate yield of pure product, with as little work as possible. Methodology research usually involves three main stages: discovery, optimisation, and studies of scope and limitations.

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The discovery requires extensive knowledge of and experience with chemical reactivities of appropriate reagents. Most complex natural products are chiral, and the bioactivity of chiral molecules varies with the enantiomer. In the later half of the twentieth century, chemists began to develop methods of stereoselective catalysis and kinetic resolution whereby reactions could be directed to produce only one enantiomer rather than a racemic mixture. Elias James Corey brought a more formal approach to synthesis design, based on retrosynthetic analysis, for which he won the Nobel Prize for Chemistry in 1990. More recently, and less widely accepted, computer programs have been written for designing a synthesis based on sequences of generic «half-reactions». Journal of the American Chemical Society.

Stereocontrolled Synthesis of a Versatile Taxane Precursor». Total Synthesis of Baccatin III and Taxol». Analysis of the reactions used for the preparation of drug candidate molecules». Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance».

Are all case study article the examples and explanations relevant to the thesis and topic-sentence ideas?
A method of super-resolution based on AAPNV A biography of manet cs.

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