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The health effects surrounding the human orgasm are diverse. In a clinical context, orgasm is usually defined strictly by the muscular contractions involved during sexual activity, how to make review of related literature with the characteristic patterns of change in heart rate, blood pressure, and often respiration rate and depth. There is some debate whether certain types of sexual sensations should be accurately classified as orgasms, including female orgasms caused by G-spot stimulation alone, and the demonstration of extended or continuous orgasms lasting several minutes or even an hour. Orgasms can be achieved by a variety of activities, including vaginal, anal or oral sex, non-penetrative sex or masturbation. A person may experience multiple orgasms.

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Scientific literature focuses on the psychology of female orgasm significantly more than it does on the psychology of male orgasm, which «appears to reflect the assumption that female orgasm is psychologically more complex than male orgasm,» but «the limited empirical evidence available suggests that male and female orgasm may bear more similarities than differences. In men, the most common way of achieving orgasm is by physical sexual stimulation of the penis. The traditional view of male orgasm is that there are two stages: emission following orgasm, almost instantly followed by a refractory period. In 1966, Masters and Johnson published pivotal research about the phases of sexual stimulation. There has been little scientific study of multiple orgasm in men. An increased infusion of the hormone oxytocin during ejaculation is believed to be chiefly responsible for the refractory period, and the amount by which oxytocin is increased may affect the length of each refractory period.

Another possible reason for the lack or absence of a refractory period in men may be an increased infusion of the hormone oxytocin. It is believed that the amount by which oxytocin is increased may affect the length of each refractory period. One misconception, particularly in older research publications, is that the vagina is completely insensitive. However, there are areas in the anterior vaginal wall and between the top junction of the labia minora and the urethra that are especially sensitive. Sex educator Rebecca Chalker states that only one part of the clitoris, the urethral sponge, is in contact with the penis, fingers, or a dildo in the vagina.

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